Herpes virus seroepidemiology in the adult Swedish population [Elektronisk resurs]
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Olsson, Jan (författare)
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Kok, Eloise (författare)
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Adolfsson, Rolf (författare)
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Lövheim, Hugo (författare)
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Elgh, Fredrik (författare)
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- Umeå universitet Medicinska fakulteten (utgivare)
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Alternativt namn: Umeå universitet. Medicinsk-odontologiska fakulteten
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Alternativt namn: Medicinska fakulteten vid Umeå universitet
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- Umeå universitet Medicinska fakulteten (utgivare)
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Alternativt namn: Umeå universitet. Medicinsk-odontologiska fakulteten
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Alternativt namn: Medicinska fakulteten vid Umeå universitet
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- Umeå universitet Medicinska fakulteten (utgivare)
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Alternativt namn: Umeå universitet. Medicinsk-odontologiska fakulteten
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Alternativt namn: Medicinska fakulteten vid Umeå universitet
- BioMed Central 2017
- Engelska.
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Ingår i: Immunity & Ageing. - 1742-4933. ; 14
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Sammanfattning
Ämnesord
Stäng
- Background: Herpes viruses establish a life-long latency and can cause symptoms during both first-time infection and later reactivation. The aim of the present study was to describe the seroepidemiology of Herpes simplex type 1 (HSV1), Herpes simplex type 2 (HSV2), Cytomegalovirus (CMV), Varicella Zoster virus (VZV) and Human herpes virus type 6 (HHV6) in an adult Swedish population (35-95 years of age). Methods: Presence of antibodies against the respective viruses in serum from individuals in the Betula study was determined with an enzyme-linked immunosorbent assay (ELISA). Singular samples from 535 persons (53.9% women, mean age at inclusion 62.7 +/- 14.4 years) collected 2003-2005 were analyzed for the five HHVs mentioned above. In addition, samples including follow-up samples collected 1988-2010 from 3,444 persons were analyzed for HSV. Results: Prevalence of HSV1 was 79.4%, HSV2 12.9%, CMV 83.2%, VZV 97.9%, and HHV6 97.5%. Herpes virus infections were more common among women (p = 0.010) and a lower age-adjusted HSV seroprevalence was found in later birth cohorts (p < 0.001). The yearly incidence of HSV infection was estimated at 14.0/1000. Conclusion: Women are more often seropositive for HHV, especially HSV2. Age-adjusted seroprevalence for HSV was lower in later birth cohorts indicating a decreasing childhood and adolescent risk of infection.
Ämnesord
- Medical and Health Sciences (hsv)
- Clinical Medicine (hsv)
- Geriatrics (hsv)
- Medicin och hälsovetenskap (hsv)
- Klinisk medicin (hsv)
- Geriatrik (hsv)
- Medical and Health Sciences (hsv)
- Clinical Medicine (hsv)
- Infectious Medicine (hsv)
- Medicin och hälsovetenskap (hsv)
- Klinisk medicin (hsv)
- Infektionsmedicin (hsv)
Indexterm och SAB-rubrik
- Herpes
- Herpes simplex
- Cytomegalovirus
- Varicella zoster virus
- Seroprevalence
- Epidemiology
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