Evaluating clinical research : all that glitters is not gold / Bengt D. Furberg and Curt D. Furberg.

• What is the purpose of this book? -- Why is benefit-to-harm balance essential to treatment decisions? -- What are the strengths of randomized controlled clinical trials? -- What are the weaknesses of randomized controlled clinical trials? -- Do meta-analyses provide the ultimate truth? -- What are the strengths of observational studies? -- What are the weaknesses of observational studies? -- Were the scientific questions stated in advance? -- Were the treatment groups comparable initially? -- Why is blinding/masking so important? -- How is symptomatic improvement measured? -- Is it really possible to assess quality of life? -- What is the value of biologic markers in drug evaluation? -- How are adverse drug reactions measured? -- How representative are study subjects in clinical trials? -- What happened to the study subjects who disappeared from the analysis? -- How reliable are active-control trials? -- How informative are composite outcomes? -- Do changes in biologic markers predict clinical benefit? -- How trustworthy are the authors? -- Does publication in a reputable scientific journal guarantee quality? -- Is it necessary to be a biostatistician to interpret scientific data? -- Are all drugs of a class interchangeable? -- How much confidence can be placed on economic analysis? -- How should I handle the massive flow of information? -- How well is research translated into clinical care?. 

Ämnesord

Medicinsk forskning  (sao)

Utvärdering  (sao)

Klinisk prövning  (sao)

Clinical trials.  (LCSH)

Clinical medicine  -- Research. (LCSH)

Medicine  -- Research. (LCSH)

Clinical Trials as Topic.  (MeSH)

Drug Evaluation.  (MeSH)

Research Design.  (MeSH)

Biomedical Research  -- methods. (MeSH)

Evaluation  (LCSH)

Clinical trials  (LCSH)

Indexterm och SAB-rubrik

V:dd Medicin: metodlära

Klassifikation

R853.C55 (LCC)

2007 K-664 (NLM)

W 20.5 (NLM)

616.0072 (DDC)

V:dd (kssb/8)