Cell detection on image-based immunoassays [Elektronisk resurs]
-
del Aguila Pla, Pol, 1990- (författare)
-
2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), Washington, DC, USA, April 4-7, 2018
-
Jaldén, Joakim, 1976- (författare)
-
KTH Skolan för elektroteknik och datavetenskap (EECS) (utgivare)
- Publicerad: IEEE, 2018
- Engelska.
-
Ingår i: 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018). - 9781538636367 - 9781538636350 ; 431-435
-
Läs hela texten
-
Läs hela texten
-
Läs hela texten
-
Läs hela texten
-
Läs hela texten
Sammanfattning
Ämnesord
Stäng
- Cell detection and counting in the image-based ELISPOT and Fluorospot immunoassays is considered a bottleneck.The task has remained hard to automatize, and biomedical researchers often have to rely on results that are not accurate.Previously proposed solutions are heuristic, and data-based solutions are subject to a lack of objective ground truth data. In this paper, we analyze a partial differential equations model for ELISPOT, Fluorospot, and assays of similar design. This leads us to a mathematical observation model forthe images generated by these assays. We use this model to motivate a methodology for cell detection. Finally, we provide a real-data example that suggests that this cell detection methodology and a human expert perform comparably.
Ämnesord
- Engineering and Technology (hsv)
- Electrical Engineering, Electronic Engineering, Information Engineering (hsv)
- Signal Processing (hsv)
- Teknik och teknologier (hsv)
- Elektroteknik och elektronik (hsv)
- Signalbehandling (hsv)
- Medical Engineering (hsv)
- Medical Image Processing (hsv)
- Medicinteknik (hsv)
- Medicinsk bildbehandling (hsv)
- Teknik och hälsa (kth)
- Technology and Health (kth)
- Electrical Engineering (kth)
- Elektro- och systemteknik (kth)
Indexterm och SAB-rubrik
- Inverse problems
- Optimization
- Source localization
- Immunoassays
Inställningar
Hjälp
Uppgift om bibliotek saknas i LIBRIS
Kontakta ditt bibliotek, eller sök utanför LIBRIS. Se högermenyn.