Metal Chelation in Medicine [Elektronisk resurs] / edited by Robert R. Crichton, Roberta J. Ward and Robert C. Hider.

• 1. Metal Toxicity : An Introduction / Robert R. Crichton -- 2. Basic Principles of Metal Chelation and Chelator Design / Robert C. Hider and Yongmin Ma -- 3. Chelation Therapy For Heavy Metals / Peter Nielsen -- 4. Treatment of Systemic Iron Overload / John Porter -- 5. Treatment of Neurodegenerative Diseases by Chelators / Roberta J. Ward, David T. Dexter and Robert R. Crichton -- 6. Chelation of Actinides / Rebecca J. Abergel -- 7. Evaluation of Iron Overload by Non-Invasive Measurement Techniques / Roland Fischer -- 8. Chelators for Diagnostic Molecular Imaging with Radioisotopes of Copper, Gallium and Zirconium / Michelle T. Ma and Philip J. Blower. 

• Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques. 

Ämnesord

Chelation therapy  (LCSH)

Chelates  (LCSH)

Klassifikation

547.59044242 (DDC)

Ucebc (kssb/8 (machine generated))