Management of MDR and XDR TB [Elektronisk resurs] / Martin Boeree.

• Contents: Management of multi drug resistance (MDR) and extensive drug resistance (XDR) TB -- Management of TB before era of drug treatment -- Surgery for TB -- Drug treatment was introduced from 1943-1963 -- Rifampicin (1963) -- Timeline: discovery of drugs for TB -- Emergence of totally drug resistant TB – Epidemiology -- Outcomes of MDR-TB treatment -- Survival curve of HIV patients with XDR TB -- Current drug treatment -- Treatment outcome in several cohorts -- Death rates in several cohorts -- Current approach for treatment of MDR/XDR TB -- WHO's programmatic management of DR TB -- Treatment recommendations -- Group 1: oral first-line agents -- Group 2: fluoroquinolones -- Group 3: injectables -- Group 4: less-effective anti-TB drugs -- Group 5: less-effective or clinical data sparse drugs -- Future drug treatment -- New compounds -- Bedaquiline (TMC207) -- The nitroimidazoles – Thioridazine -- NC-001 (PA-824, moxifloxacine, PZA) -- Dreams and realities for the future of TB treatment.

Ämnesord

Antitubercular agents.  (LCSH)

International cooperation.  (LCSH)

Multidrug-resistant tuberculosis.  (LCSH)

Tuberculosis  -- Chemotherapy. (LCSH)

Tuberculosis  -- Prevention. (LCSH)

Antitubercular Agents  -- pharmacology. (MeSH)

Extensively Drug-Resistant Tuberculosis  -- drug therapy. (MeSH)

Extensively Drug-Resistant Tuberculosis  -- prevention & control. (MeSH)

International Cooperation.  (MeSH)

Tuberculosis  -- drug therapy. (MeSH)

Tuberculosis  -- history. (MeSH)

Tuberculosis  -- prevention & control. (MeSH)

Tuberculosis, Multidrug-Resistant  -- drug therapy. (MeSH)

Tuberculosis, Multidrug-Resistant  -- prevention & control. (MeSH)