Ultrarapid synthesis of microbeads with tuneable surface probe density [Elektronisk resurs]

• We present, for the first time, a simplified and ultrarapid (~ 1s) approach for synthesis of microbeads with thiol- functionalized surfaces as potential binding sites, whose density can be tuned according to the ratio of two components in the prepolymer. We verify the successful generation of microbeads and their tuneable surface density resulted from different prepolymer off-stoichiometric ratio. This novel approach can be used for bioassays that require rapid surface capture probe binding and customized probe density for suitable bioreactions. 

Ämnesord

Medical and Health Sciences  (hsv)

Medicin och hälsovetenskap  (hsv)

Materials Science and Engineering  (kth)

Teknisk materialvetenskap  (kth)

Indexterm och SAB-rubrik

microbeads

microfluidics

off-stoichiometry thiol-ene

OSTE