Turbulent kinetic energy in the right ventricle [Elektronisk resurs] Potential MR marker for risk stratification of adults with repaired Tetralogy of Fallot
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Fredriksson, Alexandru Grigorescu (författare)
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Trzebiatowska-Krzynska, Aleksandra (författare)
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Dyverfeldt, Petter, 1980- (författare)
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Engvall, Jan (författare)
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Ebbers, Tino, 1972- (författare)
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Carlhäll, Carljohan, 1973- (författare)
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Linköpings universitet Institutionen för medicin och hälsa (utgivare)
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Linköpings universitet Medicinska fakulteten (utgivare)
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Region Östergötland Hjärt- och Medicincentrum (utgivare)
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Linköpings universitet Centrum för medicinsk bildvetenskap och visualisering, CMIV (utgivare)
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Region Östergötland Hjärt- och Medicincentrum (utgivare)
- Publicerad: Hoboken : John Wiley & Sons, 2018
- Engelska.
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Ingår i: Journal of Magnetic Resonance Imaging. - 1053-1807. ; 47:4, 1043-1053
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- Relaterad länk:
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http://www.liu.se (Värdpublikation)
Sammanfattning
Ämnesord
Stäng
- Purpose: To assess right ventricular (RV) turbulent kinetic energy (TKE) in patients with repaired Tetralogy of Fallot (rToF) and a spectrum of pulmonary regurgitation (PR), as well as to investigate the relationship between these 4D flow markers and RV remodeling. Materials and Methods: Seventeen patients with rToF and 10 healthy controls were included in the study. Patients were divided into two groups based on PR fraction: one lower PR fraction group (11%) and one higher PR fraction group (>11%). Field strength/sequences: 3D cine phase contrast (4D flow), 2D cine phase contrast (2D flow), and balanced steady-state free precession (bSSFP) at 1.5T. Assessment: The RV volume was segmented in the morphologic short-axis images and TKE parameters were computed inside the segmented RV volume throughout diastole. Statistical tests: One-way analysis of variance with Bonferroni post-hoc test; unpaired t-test; Pearson correlation coefficients; simple and stepwise multiple regression models; intraclass correlation coefficient (ICC). Results: The higher PR fraction group had more remodeled RVs (140 6 25 vs. 107 6 22 [lower PR fraction, P < 0.01] and 93 6 15 ml/m2[healthy, P < 0.001] for RV end-diastolic volume index [RVEDVI]) and higher TKE values (5.95 6 3.15 vs. 2.23 6 0.81 [lower PR fraction, P < 0.01] and 1.91 6 0.78 mJ [healthy, P < 0.001] for Peak Total RV TKE). Multiple regression analysis between RVEDVI and 4D/2D flow parameters showed that Peak Total RV TKE was the strongest predictor of RVEDVI (R25 0.47, P 5 0.002). Conclusion: The 4D flow-specific TKE markers showed a slightly stronger association with RV remodeling than conventional 2D flow PR parameters. These results suggest novel hemodynamic aspects of PR in the development of late complications after ToF repair.
Ämnesord
- Medical and Health Sciences (hsv)
- Clinical Medicine (hsv)
- Radiology, Nuclear Medicine and Medical Imaging (hsv)
- Medicin och hälsovetenskap (hsv)
- Klinisk medicin (hsv)
- Radiologi och bildbehandling (hsv)
- Medical and Health Sciences (hsv)
- Clinical Medicine (hsv)
- Cardiac and Cardiovascular Systems (hsv)
- Medicin och hälsovetenskap (hsv)
- Klinisk medicin (hsv)
- Kardiologi (hsv)
- Engineering and Technology (hsv)
- Medical Engineering (hsv)
- Medical Laboratory and Measurements Technologies (hsv)
- Teknik och teknologier (hsv)
- Medicinteknik (hsv)
- Medicinsk laboratorie- och mätteknik (hsv)
- Medical and Health Sciences (hsv)
- Clinical Medicine (hsv)
- Anesthesiology and Intensive Care (hsv)
- Medicin och hälsovetenskap (hsv)
- Klinisk medicin (hsv)
- Anestesi och intensivvård (hsv)
- Engineering and Technology (hsv)
- Medical Engineering (hsv)
- Medical Image Processing (hsv)
- Teknik och teknologier (hsv)
- Medicinteknik (hsv)
- Medicinsk bildbehandling (hsv)
Genre
- government publication (marcgt)
Indexterm och SAB-rubrik
- 4D flow
- MRI
- Turbulence
- Tetralogy of Fallot
- Turbulent kinetic energy
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