Functional properties of low-modulus PMMA bone cements containing linoleic acid [Elektronisk resurs]
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Robo, Céline (författare)
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Wenner, David (författare)
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Ubhayasekera, S. J. Kumari A. (författare)
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Hilborn, Jöns, 1956- (författare)
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Öhman-Mägi, Caroline (författare)
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Persson, Cecilia (författare)
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Uppsala universitet Teknisk-naturvetenskapliga vetenskapsområdet (utgivare)
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Uppsala universitet Teknisk-naturvetenskapliga vetenskapsområdet (utgivare)
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Uppsala universitet Teknisk-naturvetenskapliga vetenskapsområdet (utgivare)
- Publicerad: 2021
- Engelska.
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Ingår i: Journal of Functional Biomaterials. - 2079-4983. ; 12:1
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Sammanfattning
Ämnesord
Stäng
- Acrylic bone cements modified with linoleic acid are a promising low-modulus alternative to traditional high-modulus bone cements. However, several key properties remain unexplored, including the effect of autoclave sterilization and the potential use of low-modulus cements in other applications than vertebral augmentation. In this work, we evaluate the effect of sterilization on the structure and stability of linoleic acid, as well as in the handling properties, glass transition temperature, mechanical properties, and screw augmentation potential of low-modulus cement containing the fatty acid. Neither 1 H NMR nor SFC-MS/MS analysis showed any detectable differences in autoclaved linoleic acid compared to fresh one. The peak polymerization temperature of the low-modulus cement was much lower (28–30 °C) than that of the high-modulus cement (67 °C), whereas the setting time remained comparable (20–25 min). The T g of the low-modulus cement was lower (75–78 °C) than that of the high-stiffness cement (103 °C). It was shown that sterilization of linoleic acid by autoclaving did not significantly affect the functional properties of low-modulus PMMA bone cement, making the component suitable for sterile production. Ultimately, the low-modulus cement exhibited handling and mechanical properties that more closely match those of osteoporotic vertebral bone with a screw holding capacity of under 2000 N, making it a promising alternative for use in combination with orthopedic hardware in applications where high-stiffness augmentation materials can result in undesired effects.
Ämnesord
- Engineering and Technology (hsv)
- Materials Engineering (hsv)
- Teknik och teknologier (hsv)
- Materialteknik (hsv)
- Engineering and Technology (hsv)
- Medical Engineering (hsv)
- Medical Materials (hsv)
- Teknik och teknologier (hsv)
- Medicinteknik (hsv)
- Medicinska material och protesteknik (hsv)
- Teknisk fysik med inriktning mot materialvetenskap (uu)
- Engineering Science with specialization in Materials Science (uu)
Genre
- government publication (marcgt)
Indexterm och SAB-rubrik
- Acrylic bone cement
- low-modulus
- mechanical properties
- bending
- vertebroplasty
- screw
- pullout
- sterilization
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Journal of Functional Biomaterials