High levels of DDT in breast milk: Intake, risk, lactation duration, and involvement of gender [Elektronisk resurs]

• We investigated presence and levels of DDT in 163 breast milk samples from four South African villages where, in three of them, malaria is controlled with DDT-sprayed indoors. Mean Sigma DDT levels in breast milk were 18, 11, and 9.5 mg/kg mf (milk fat) from the three DDT-sprayed villages, respectively, including the highest Sigma DDT level ever reported for breast milk from South Africa (140 mg/kg mf). Understanding the causes for these differences would be informative for exposure reduction intervention. The Provisional Tolerable Daily Intake (PTDI) for DDT by infants, and the Maximum Residue Limit (MRL) were significantly exceeded. DDT had no effect on duration of lactation. There were indications (not significant) from DDT-sprayed villages that first-born female infants drink milk with more Sigma DDT than first-born male infants, and vice versa for multipara male and female infants, suggesting gender involvement on levels of DDT in breast milk - requiring further investigation. 

Ämnesord

Medical and Health Sciences  (hsv)

Health Sciences  (hsv)

Environmental Health and Occupational Health  (hsv)

Medicin och hälsovetenskap  (hsv)

Hälsovetenskaper  (hsv)

Miljömedicin och yrkesmedicin  (hsv)

Natural Sciences  (hsv)

Earth and Related Environmental Sciences  (hsv)

Environmental Sciences  (hsv)

Naturvetenskap  (hsv)

Geovetenskap och miljövetenskap  (hsv)

Miljövetenskap  (hsv)

Natural Sciences  (hsv)

Chemical Sciences  (hsv)

Analytical Chemistry  (hsv)

Naturvetenskap  (hsv)

Kemi  (hsv)

Analytisk kemi  (hsv)

NATURAL SCIENCES  (svep)

NATURVETENSKAP  (svep)

Indexterm och SAB-rubrik

Breast milk

South Africa

Malaria control

Indoor residual spray

Maximum Residue Limit

Provisional Tolerable Daily Intake