Skeletal Function and Form [Elektronisk resurs] Mechanobiology of Skeletal Development, Aging, and Regeneration / Dennis R. Carter, Gary S. Beaupré.

• 1. Form and function: -- Historical function -- Skeletal pattern formation -- Skeletal evolution -- Human skeletal growth and functional adaptation -- 2. Skeletal tissue histomorphology and mechanics: -- Cartilage -- Bone -- Tendons and ligaments -- Levels of consideration in mechanobiology -- Stress and strain -- Structural mechanics and stress analysis -- 3. Cartilage differentiation and growth: -- Tendon development and fibrocartilage metaplasia -- Secondary cartilage -- Joint surface morphogenesis -- 4. Perichondral and periosteal ossification: -- Bone formation -- Biological and mechanobiological factors -- Mathematical model for growth and adaptation -- Creating a more complete model -- 5. Endochondral growth and ossification: -- Morphology and biology -- Biological factors -- Mechanobiological regulation of growth and ossification patterns -- Mechanobiology and endochonral ossification patterns -- 6. Cancellous bone: -- Biology and morphology -- A continuum model approach for mechanically regulated remodeling -- Normal development and adaptation of cancellous bone architecture -- Functional adaptation caused by changes in physical activities -- Modifications in bone structure by biological factors -- Bone remodeling around implants -- Creating a more complex model -- 7. Skeletal tissue regeneration: -- Biology and mechanobiology -- The bone-implant interface -- Fracture healing -- Cyclic compression osteogenesis vs. distraction osteogenesis -- Neochondrogenesis and joint repair -- 8. Articular cartilage development and destruction: -- Growth and ossification near joint surfaces -- Articular cartilage development and maintenance -- Joint adaptation and aging -- Osteoarthritis -- 9. Mechanobiology in skeletal evolution: -- Bone scaling and developmental mechanics -- Scaling influences on joints -- Long bone cross sections in different taxa -- Bony epiphyses and growth plates -- 10. The physical nature of living things -- Appendix A: Material characteristics -- Appendix B: Structural characteristics -- Appendix C: Failure characteristics.

• The intimate relationship between form and function inherent in the design of animals is perhaps nowhere more evident than in the musculoskeletal system. This book, about how function determines form, addresses the role of mechanical factors in the development, adaptation, maintenance, aging, and repair of skeletal tissues. The authors refer to this process as mechanobiology and develop their theme within an evolutionary framework. They show how degenerative disorders such as arthritis and osteoporosis are regulated by the same mechanical processes that influence normal development and growth. Skeletal Function and Form bridges important gaps among disciplines, providing a common ground for a multidisciplinary understanding. 

Ämnesord

Biomechanics.  (LCSH)

Bone regeneration.  (LCSH)

Cartilage.  (LCSH)

Musculoskeletal system.  (LCSH)

Biomechanics.  (LCSH)

Bone Regeneration.  (LCSH)

Cartilage.  (LCSH)

Bone  -- Growth. (LCSH)

Bone Development  -- physiology. (LCSH)

Klassifikation

612.7/5 (DDC)

Ven (kssb/8 (machine generated))