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Atrial function and loading conditions in athletes / Flavio D'Ascenzi

D'Ascenzi, Flavio, 1983- (författare)
Umeå universitet. Institutionen för folkhälsa och klinisk medicin (utgivare)
Alternativt namn: Umeå University. Department of Public Health and Clinical Medicine
ISBN 978-91-7601-715-9
Umeå : Umeå University, 2017
Engelska 100 s.
Serie: [Umeå University medical dissertations], 0346-6612 ; N.S., 1898
  • BokAvhandling(Diss. (sammanfattning) Umeå : Umeå universitet, 2017)
Sammanfattning Ämnesord
Stäng  
  • Intensive training is associated with hemodynamic changes that typically induce an enlargement of cardiac chamber. Despite LA dilatation in athletes has been interpreted as a benign adaptation, little evidence is available. The aim of this thesis is to demonstrate that LA size changes in response to alterations in loading conditions and to analyse atrial myocardial function in athletes through the application of novel echocardiographic techniques. We found that top-level athletes exhibit a dynamic morphological and functional LA remodelling, induced by training, with an increase in reservoir and conduit volumes, but stable active volume. Training causes an increase in biatrial volumes which is accompanied by normal filling pressures and stiffness. These changes in atrial morphology are not associated with respective electrical changes. Extending the evidence from adult athletes to children, we found that training-induced atrial remodelling can occur in the early phases of the sports career and is associated with a preserved biatrial function. Finally, in a meta-analysis study of the available evidence we demonstrated that atrial function and size are not affected by aging. In conclusions, athlete’s heart is characterized by a physiological biatrial enlargement. This adaptation occurs in close association with LV cavity enlargement, is dynamic and reversible. This increase in biatrial size is not intrinsically an expression of atrial dysfunction. Indeed, in athletes the atria are characterized by a preserved reservoir function, normal myocardial stiffness, and dynamic changes in response to different loading conditions. 

Ämnesord

Action potentials  (MeSH)
Athletes  (MeSH)
Atrial function, left  -- physiology (MeSH)
Atrial function, right  (MeSH)
Cardiomegaly, exercise-induced  (MeSH)
Heart conduction system  -- physiology (MeSH)
Heart rate  (MeSH)
Physical education and training  (MeSH)
Soccer  -- physiology (MeSH)

Indexterm och SAB-rubrik

Athlete's heart
Training
Exercise
Speckle-tracking echocardiography
Atrial strain
Atrial deformation

Klassifikation

612.17 (DDC)
Veh (kssb/8 (machine generated))
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